Percodan Abuse and Drug Interactions

Percodan Abuse and Drug InteractionsPercodan is a prescription pain medication commonly used to relieve moderate to severe pain. It works through the combination of aspirin, a salicylate, and oxycodone, an opiate. The combination of the two medications can create soothing sensations throughout the body and help alleviate pain. The aspirin works to keep the user’s brain from creating COX-2 enzymes that produce prostaglandins, which control inflammation, pain signals and the functions of certain organs such as the liver. Once this chemical production ceases, the oxycodone travels through the body to numb the central nervous system and create a euphoric response.

Dangers of Combining Percodan with Drugs and Alcohol

As Percodan works to shut down pain receptors in the brain and numb the central nervous system, it can make it challenging for other drugs to incorporate into the user’s system, and severe drug interactions can occur. Percodan can lead to dangerous interactions when combined with a number of substances, including the following:

  • NSAIDs – Non-steroidal anti-inflammatory drugs, also known as NSAIDs, are medications such as Aleve, Tylenol, Ibuprofen or Excedrin. Like aspirin, the main purpose of these medications is to block COX-2 enzymes in the brain and stop production of prostaglandins. The reason that this drug interaction can be dangerous is that combining Percodan and NSAIDs may cause the body’s natural defense mechanism to surrender and stop providing protection to the organs of the body. This can make the user’s body prone to organ failure, especially in the stomach where the lining can become thin and cause bleeding.
  • Narcotics – Mixing narcotics with other narcotics can be dangerous, as these drugs work against normal brain chemistry and often replace natural brain functions, such as the production of endorphins. Many narcotics work to break down endorphins in the brain, which can leave the user continually dependent on the drug.
  • Alcohol – Alcohol can intensify some effects of Percodan, such as dizziness and drowsiness. This can be harmful as users may fall asleep at inopportune times and find themselves with a lack of balance, which could lead to injury. When Percodan is combined with alcohol, it can also cause damage to the organs, especially the liver. Since the aspirin in Percodan works to halt the production of the organ-protecting prostaglandins, the liver is at risk for damage. Not only is the liver left unprotected, but it is also being threatened by the presence of alcohol, which it views as a poison. Mixing alcohol and Percodan can also be detrimental to the heart, stomach and kidneys.

Many Percodan users find themselves asking which medications they are able to combine with the drug. Doctors and therapists can often help by providing information on how to avoid negative drug interactions. The safest way to prevent a harmful or lethal drug interaction with Percodan is to avoid combining it with any other prescription drug or addictive substance. It can be beneficial to speak to your doctor or pharmacist to learn more details on the dangers of drug and alcohol interaction related to Percodan use.

Finding Help for Percodan Abuse Problems

If you or someone you love is struggling with Percodan abuse, please call our toll-free helpline now. Our counselors are available 24 hours a day to answer your questions about Percodan abuse and drug interactions. We can help you avoid dangerous complications and safely recover from a Percodan addiction. Please call now.